Taking into account the progress in the DM field, IDMC 10 programme will be structured around the 5 below topics:
Session 1 : Mutation, genetics and epigenetics This session covers all aspects of the mutations associated with DM, including population genetics, particularities of the mutations, epigenetic modifications and repeat instability mechanisms.
Session 2 : Clinical and social issues This session covers all clinical aspects in different organ systems, diagnosis, as well as ethical and social issues in DM patients and families.
Session 3 : Disease mechanisms This session covers the research devoted to understand DM disease mechanisms in various model systems (in vitro, cells, animal models), with exception of repeat instability mechanisms covered in Session 1.
Session 4 : Therapeutic development This session covers the development of new therapeutic strategies, from proof-of-principle experiments in test tubes and cell models, to preclinical assays in animals.
Session 5 : Biomarkers / outcome measures / registrie / therapeutic assays This session covers aspects directly linked with therapeutic development in human patients. It includes the characterisation of biomarkers and outcome measures, the development of registries and databases, as well as updates on ongoing clinical assays.